{"id":330386,"date":"2020-12-31T13:00:22","date_gmt":"2020-12-31T12:00:22","guid":{"rendered":"http:\/\/kapitalis.com\/tunisie\/?p=330386"},"modified":"2020-12-31T13:00:25","modified_gmt":"2020-12-31T12:00:25","slug":"le-vaccin-anti-covid-en-10-questions-reponses","status":"publish","type":"post","link":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/","title":{"rendered":"Le vaccin anti-Covid en 10 questions-r\u00e9ponses"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

\u00c0 l\u2019aube de la nouvelle ann\u00e9e 2021, plusieurs pays se sont munis d\u2019une nouvelle arme face \u00e0 cette pand\u00e9mie du coronavirus (Covid-19), en d\u00e9butant leur campagne vaccinale d\u00e8s le mois de d\u00e9cembre; l\u2019objectif \u00e9tant d\u2019\u00e9viter les d\u00e9c\u00e8s et les hospitalisations en prot\u00e9geant les personnes \u00e0 risque. \u00c0 l\u2019oppos\u00e9, la Tunisie conc\u00e8de un retard inadmissible pour se procurer le premier arrivage du vaccin qui sera, selon l\u2019accord conclu avec le laboratoire am\u00e9ricain Pfizer, disponible durant le 2e trimestre 2021.<\/em><\/strong><\/p>\n\n\n\n

Par Dr Taha Abdelkader Allouche<\/strong> *<\/p>\n\n\n\n\n\n\n\n

\"\"<\/figure><\/div>\n\n\n\n

Le principe de la vaccination contre la Covid-19 est de permettre au syst\u00e8me immunitaire de d\u00e9clencher une r\u00e9ponse immune sp\u00e9cifique contre le virus et de le neutraliser avant de d\u00e9velopper la maladie. La majorit\u00e9 des vaccins en d\u00e9veloppement ciblent la prot\u00e9ine Spike du virus, aussi appel\u00e9e prot\u00e9ine S, qui joue un r\u00f4le primordial dans l\u2019infection. Cette prot\u00e9ine est situ\u00e9e \u00e0 la surface de l\u2019enveloppe du virus et lui permet de se fixer \u00e0 un r\u00e9cepteur cellulaire (ACE2) puis de p\u00e9n\u00e9trer dans les cellules.<\/p>\n\n\n\n

Quels sont les diff\u00e9rents types de vaccins contre la Covid-19 ?<\/em><\/strong><\/p>\n\n\n\n

Elles sont de 2 types :<\/p>\n\n\n\n

*Les technologies classiques<\/em>, bas\u00e9es sur l\u2019utilisation d\u2019un virus entier et inactiv\u00e9, (les vaccins d\u00e9velopp\u00e9s par des consortiums chinois), ou d\u2019une partie seulement du virus (la prot\u00e9ine S) associ\u00e9 \u00e0 un adjuvant de l\u2019immunit\u00e9 (vaccins de Sanofi-GSK).
*Les \u00abnouvelles\u00bb technologies<\/em>, bas\u00e9es sur : 1- l\u2019utilisation d\u2019ARNm, c\u2019est-\u00e0-dire la s\u00e9quence g\u00e9n\u00e9tique de la prot\u00e9ine S (vaccins \u00e0 ARNm d\u00e9velopp\u00e9s par Moderna et par Pfizer-BioNTech); 2- l\u2019utilisation d\u2019un vecteur viral dans le g\u00e9nome duquel on a ins\u00e9r\u00e9 le g\u00e8ne de la prot\u00e9ine S du virus. Le vecteur le plus utilis\u00e9 est l\u2019ad\u00e9novirus du chimpanz\u00e9 (vaccins d\u00e9velopp\u00e9s par l\u2019Universit\u00e9 d\u2019Oxford-AstraZeneca, Spoutnik V d\u00e9velopp\u00e9 en Russie et CanSinoBio d\u00e9velopp\u00e9 en Chine).<\/p>\n\n\n\n

Modus operandi et efficacit\u00e9 des vaccins \u00e0 ARNm (Pfizer-BioNTech et de Moderna) ?
<\/em><\/strong>L\u2019ARNm vaccinal, une fois inject\u00e9 dans un muscle, p\u00e9n\u00e9trera dans les cellules et sera traduit dans le cytoplasme en prot\u00e9ine S. Cette expression va d\u00e9clencher la production d\u2019anticorps neutralisants par les lymphocytes B, une r\u00e9ponse lymphocytaire T cytotoxique permettant de d\u00e9truire les cellules infect\u00e9es par le virus et, surtout, la g\u00e9n\u00e9ration de lymphocytes T m\u00e9moire tr\u00e8s pr\u00e9cieux en cas de rencontre ult\u00e9rieure avec le coronavirus.
Les preuves d\u2019efficacit\u00e9 de ces vaccins proviennent de deux vastes essais cliniques de phase 3 randomis\u00e9s, en double aveugle et avec un groupe placebo, lui procurant le plus haut niveau de preuve scientifique, montrant une efficacit\u00e9 respective de 95% et de 94%.<\/p>\n\n\n\n

Les mutations impactent-elles l\u2019efficacit\u00e9 des vaccins \u00e0 ARNm ?
<\/em><\/strong>Si les mutations touchent la prot\u00e9ine S du virus d\u2019une fa\u00e7on significative affectant la capacit\u00e9 du syst\u00e8me immunitaire \u00e0 la reconna\u00eetre, alors l\u2019efficacit\u00e9 des vaccins actuellement d\u00e9velopp\u00e9s pourrait \u00eatre diminu\u00e9e.<\/p>\n\n\n\n

Quel d\u00e9lai respecter entre les 2 injections du vaccin Pfizer-BioNTech ?
<\/em><\/strong>Le sch\u00e9ma vaccinal comporte 2 doses administr\u00e9es par voie intramusculaire, \u00e0 3 semaines d\u2019intervalle. La 2e dose peut \u00eatre administr\u00e9e entre le 17e et le 21e jour. Si par erreur elle \u00e9tait faite avant le 17e jour, il ne serait n\u00e9anmoins pas n\u00e9cessaire de la r\u00e9p\u00e9ter. Si plus de 21 jours se sont \u00e9coul\u00e9s depuis la premi\u00e8re dose, la deuxi\u00e8me dose doit \u00eatre administr\u00e9e d\u00e8s que possible, mais il n\u2019y a pas besoin de faire en tout plus que 2 doses. Si l\u2019on est expos\u00e9 au virus avant la 2e dose, on a une forte chance d\u2019\u00eatre prot\u00e9g\u00e9 estim\u00e9e \u00e0 50% mais seule une vaccination compl\u00e8te avec 2 doses vaccinales offre une protection de l\u2019ordre de 95%.<\/p>\n\n\n\n

Les avantages et les inconv\u00e9nients des vaccins ARNm ?<\/em><\/strong><\/p>\n\n\n\n

La synth\u00e8se est faite d\u2019une fa\u00e7on facile et rapide sans avoir besoin de manipuler le virus. La prot\u00e9ine S est produite dans nos cellules de fa\u00e7on naturelle; elle prend donc la conformation (la forme) qu\u2019elle a habituellement et induit une r\u00e9ponse immunitaire compl\u00e8te (anticorps et lymphocytaire T). C\u2019est un avantage par rapport aux vaccins inactiv\u00e9s ou sous-unitaires qui induisent une r\u00e9ponse immunitaire uniquement de type anticorps.<\/p>\n\n\n\n

Le gros b\u00e9mol du vaccin annonc\u00e9 par BioNTech et Pfizer ce sont les conditions de sa conservation ?<\/em><\/strong><\/p>\n\n\n\n

Le vaccin doit \u00eatre imp\u00e9rativement maintenu \u00e0 temp\u00e9rature constante de -70 degr\u00e9s, n\u00e9cessitant toute une logistique appropri\u00e9e. Ceci constitue un d\u00e9savantage concurrentiel notoire pour le laboratoire. Par comparaison, le vaccin de Moderna reste stable entre 2\u00b0 C et 8\u00b0 C, la temp\u00e9rature d\u2019un r\u00e9frig\u00e9rateur standard, pendant 30 jours.<\/p>\n\n\n\n

Les vaccins \u00e0 ARNm peuvent-ils modifier nos g\u00e8nes ?<\/em><\/strong><\/p>\n\n\n\n

Lors de la synth\u00e8se prot\u00e9ique, l\u2019information circule dans le sens ADN\u2192ARN\u2192prot\u00e9ine. Il n\u2019y pas dans notre organisme d\u2019enzyme permettant d\u2019inverser ce sens. Ainsi, les vaccins ARNm ne peuvent pas modifier nos g\u00e8nes (qui eux sont sous forme d\u2019ADN).<\/p>\n\n\n\n

Quels sont les effets secondaires les plus fr\u00e9quents des vaccins \u00e0 ARNm?<\/em><\/strong><\/p>\n\n\n\n

La grande majorit\u00e9 des effets secondaires observ\u00e9s lors des essais cliniques se manifestent le lendemain de la vaccination et durent habituellement moins de 3 jours. Ils sont classiques et relativement attendus et fr\u00e9quents : rougeur au point d\u2019injection, fatigue, maux de t\u00eate, douleurs musculaires, frissons, fi\u00e8vre et ad\u00e9nopathie axillaire. Les effets g\u00e9n\u00e9raux sont plus fr\u00e9quents apr\u00e8s la 2e dose de vaccin et chez les jeunes.<\/p>\n\n\n\n

Quel d\u00e9lai respecter entre un ant\u00e9c\u00e9dent de Covid-19 et la vaccination ?<\/em><\/strong><\/p>\n\n\n\n

Il appara\u00eet que la r\u00e9infection est tr\u00e8s peu fr\u00e9quente dans les 90 jours suivant l\u2019infection initiale. On recommande donc que les personnes ayant une infection aigu\u00eb Covid-19 soient vaccin\u00e9es apr\u00e8s ce d\u00e9lai de 90 jours.<\/p>\n\n\n\n

Devra-t-on se faire vacciner tous les ans comme pour la grippe ?<\/em><\/strong><\/p>\n\n\n\n

Si le virus acquiert des mutations lui permettant de ne plus \u00eatre reconnu par une personne qui a d\u00e9j\u00e0 fait la maladie ou qui a \u00e9t\u00e9 vaccin\u00e9e. Il est possible que la Covid-19 devienne une maladie \u00e0 recrudescence saisonni\u00e8re comme la grippe. Il sera alors n\u00e9cessaire de se vacciner r\u00e9guli\u00e8rement avec un vaccin adapt\u00e9 aux nouveaux variants.<\/p>\n\n\n\n

Le vaccin permet-il d\u2019arr\u00eater l\u2019\u00e9pid\u00e9mie ?<\/em><\/strong><\/p>\n\n\n\n

Les essais cliniques des vaccins \u00e0 ARN approuv\u00e9s ont \u00e9t\u00e9 \u00e9labor\u00e9s afin de d\u00e9montrer une efficacit\u00e9 contre la maladie Covid-19. Si les premiers r\u00e9sultats sont en faveur d\u2019une excellente efficacit\u00e9 contre les \u00e9pisodes symptomatiques de la maladie et contre ses formes graves, il n\u2019y a pas encore de r\u00e9sultats concernant la protection contre l\u2019infection asymptomatique par le virus ou sa transmissibilit\u00e9. Si cela vient d\u2019\u00eatre d\u00e9montr\u00e9, il sera alors int\u00e9ressant d\u2019atteindre un certain seuil de couverture vaccinale afin de favoriser l\u2019immunit\u00e9 de groupe, et ainsi prot\u00e9ger indirectement les personnes qui ne peuvent pas \u00eatre vaccin\u00e9es, voire permettre l\u2019interruption de l\u2019\u00e9pid\u00e9mie.<\/p>\n\n\n\n

* M\u00e9decin et activiste politique.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

\u00c0 l\u2019aube de la nouvelle ann\u00e9e 2021, plusieurs pays se sont munis d\u2019une nouvelle arme face \u00e0 cette pand\u00e9mie du coronavirus (Covid-19), en d\u00e9butant leur campagne vaccinale d\u00e8s le mois de d\u00e9cembre; l\u2019objectif \u00e9tant d\u2019\u00e9viter les d\u00e9c\u00e8s et les hospitalisations en prot\u00e9geant les personnes \u00e0 risque. \u00c0 l\u2019oppos\u00e9, la Tunisie conc\u00e8de un retard inadmissible pour…<\/p>\n","protected":false},"author":8,"featured_media":330387,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[992,998,1000,2433],"tags":[86166,86169,73060,75291,77264,86167,85373,86168],"class_list":["post-330386","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-a-la-une","category-societe","category-tribune","category-tunisie","tag-campagne-vaccinale","tag-cansinobio","tag-coronavirus","tag-covid-19","tag-moderna","tag-oxford-astrazeneca","tag-pfizer-biontech","tag-spoutnik-v"],"yoast_head":"\nLe vaccin anti-Covid en 10 questions-r\u00e9ponses - Kapitalis<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Le vaccin anti-Covid en 10 questions-r\u00e9ponses - Kapitalis\" \/>\n<meta property=\"og:description\" content=\"\u00c0 l\u2019aube de la nouvelle ann\u00e9e 2021, plusieurs pays se sont munis d\u2019une nouvelle arme face \u00e0 cette pand\u00e9mie du coronavirus (Covid-19), en d\u00e9butant leur campagne vaccinale d\u00e8s le mois de d\u00e9cembre; l\u2019objectif \u00e9tant d\u2019\u00e9viter les d\u00e9c\u00e8s et les hospitalisations en prot\u00e9geant les personnes \u00e0 risque. \u00c0 l\u2019oppos\u00e9, la Tunisie conc\u00e8de un retard inadmissible pour...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/\" \/>\n<meta property=\"og:site_name\" content=\"Kapitalis\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/KapitalisInfo\/\" \/>\n<meta property=\"article:published_time\" content=\"2020-12-31T12:00:22+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-12-31T12:00:25+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/kapitalis.com\/tunisie\/wp-content\/uploads\/2022\/05\/kapitalis-logo-fb.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"630\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"webmaster kapitalis\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@KapitalisInfo\" \/>\n<meta name=\"twitter:site\" content=\"@KapitalisInfo\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"webmaster kapitalis\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/\"},\"author\":{\"name\":\"webmaster kapitalis\",\"@id\":\"https:\/\/kapitalis.com\/tunisie\/#\/schema\/person\/d71f33a9ca44f7bad4698210b480c8e9\"},\"headline\":\"Le vaccin anti-Covid en 10 questions-r\u00e9ponses\",\"datePublished\":\"2020-12-31T12:00:22+00:00\",\"dateModified\":\"2020-12-31T12:00:25+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/\"},\"wordCount\":1223,\"commentCount\":13,\"publisher\":{\"@id\":\"https:\/\/kapitalis.com\/tunisie\/#organization\"},\"image\":{\"@id\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#primaryimage\"},\"thumbnailUrl\":\"\",\"keywords\":[\"campagne vaccinale\",\"CanSinoBio\",\"Coronavirus\",\"Covid-19\",\"Moderna\",\"Oxford-AstraZeneca\",\"Pfizer\/BioNTech\",\"Spoutnik V\"],\"articleSection\":[\"A LA UNE\",\"SOCIETE\",\"TRIBUNE\",\"Tunisie\"],\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/\",\"url\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/\",\"name\":\"Le vaccin anti-Covid en 10 questions-r\u00e9ponses - Kapitalis\",\"isPartOf\":{\"@id\":\"https:\/\/kapitalis.com\/tunisie\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#primaryimage\"},\"thumbnailUrl\":\"\",\"datePublished\":\"2020-12-31T12:00:22+00:00\",\"dateModified\":\"2020-12-31T12:00:25+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#primaryimage\",\"url\":\"\",\"contentUrl\":\"\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/kapitalis.com\/tunisie\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Le vaccin anti-Covid en 10 questions-r\u00e9ponses\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/kapitalis.com\/tunisie\/#website\",\"url\":\"https:\/\/kapitalis.com\/tunisie\/\",\"name\":\"Kapitalis\",\"description\":\"L'actualit\u00e9 en Tunisie et dans le monde\",\"publisher\":{\"@id\":\"https:\/\/kapitalis.com\/tunisie\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/kapitalis.com\/tunisie\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/kapitalis.com\/tunisie\/#organization\",\"name\":\"Kapitalis\",\"url\":\"https:\/\/kapitalis.com\/tunisie\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/kapitalis.com\/tunisie\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/kapitalis.com\/tunisie\/wp-content\/uploads\/2022\/05\/Kapitalis-big-size.png\",\"contentUrl\":\"https:\/\/kapitalis.com\/tunisie\/wp-content\/uploads\/2022\/05\/Kapitalis-big-size.png\",\"width\":5000,\"height\":1500,\"caption\":\"Kapitalis\"},\"image\":{\"@id\":\"https:\/\/kapitalis.com\/tunisie\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/KapitalisInfo\/\",\"https:\/\/x.com\/KapitalisInfo\",\"https:\/\/www.youtube.com\/channel\/UC-yDYrHyfFBWWZaOw3FPg9Q\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/kapitalis.com\/tunisie\/#\/schema\/person\/d71f33a9ca44f7bad4698210b480c8e9\",\"name\":\"webmaster kapitalis\",\"url\":\"https:\/\/kapitalis.com\/tunisie\/author\/webmaster-kapitalis\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Le vaccin anti-Covid en 10 questions-r\u00e9ponses - Kapitalis","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/","og_locale":"fr_FR","og_type":"article","og_title":"Le vaccin anti-Covid en 10 questions-r\u00e9ponses - Kapitalis","og_description":"\u00c0 l\u2019aube de la nouvelle ann\u00e9e 2021, plusieurs pays se sont munis d\u2019une nouvelle arme face \u00e0 cette pand\u00e9mie du coronavirus (Covid-19), en d\u00e9butant leur campagne vaccinale d\u00e8s le mois de d\u00e9cembre; l\u2019objectif \u00e9tant d\u2019\u00e9viter les d\u00e9c\u00e8s et les hospitalisations en prot\u00e9geant les personnes \u00e0 risque. \u00c0 l\u2019oppos\u00e9, la Tunisie conc\u00e8de un retard inadmissible pour...","og_url":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/","og_site_name":"Kapitalis","article_publisher":"https:\/\/www.facebook.com\/KapitalisInfo\/","article_published_time":"2020-12-31T12:00:22+00:00","article_modified_time":"2020-12-31T12:00:25+00:00","og_image":[{"width":1200,"height":630,"url":"https:\/\/kapitalis.com\/tunisie\/wp-content\/uploads\/2022\/05\/kapitalis-logo-fb.png","type":"image\/png"}],"author":"webmaster kapitalis","twitter_card":"summary_large_image","twitter_creator":"@KapitalisInfo","twitter_site":"@KapitalisInfo","twitter_misc":{"\u00c9crit par":"webmaster kapitalis","Dur\u00e9e de lecture estim\u00e9e":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#article","isPartOf":{"@id":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/"},"author":{"name":"webmaster kapitalis","@id":"https:\/\/kapitalis.com\/tunisie\/#\/schema\/person\/d71f33a9ca44f7bad4698210b480c8e9"},"headline":"Le vaccin anti-Covid en 10 questions-r\u00e9ponses","datePublished":"2020-12-31T12:00:22+00:00","dateModified":"2020-12-31T12:00:25+00:00","mainEntityOfPage":{"@id":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/"},"wordCount":1223,"commentCount":13,"publisher":{"@id":"https:\/\/kapitalis.com\/tunisie\/#organization"},"image":{"@id":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#primaryimage"},"thumbnailUrl":"","keywords":["campagne vaccinale","CanSinoBio","Coronavirus","Covid-19","Moderna","Oxford-AstraZeneca","Pfizer\/BioNTech","Spoutnik V"],"articleSection":["A LA UNE","SOCIETE","TRIBUNE","Tunisie"],"inLanguage":"fr-FR","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/","url":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/","name":"Le vaccin anti-Covid en 10 questions-r\u00e9ponses - Kapitalis","isPartOf":{"@id":"https:\/\/kapitalis.com\/tunisie\/#website"},"primaryImageOfPage":{"@id":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#primaryimage"},"image":{"@id":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#primaryimage"},"thumbnailUrl":"","datePublished":"2020-12-31T12:00:22+00:00","dateModified":"2020-12-31T12:00:25+00:00","breadcrumb":{"@id":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/"]}]},{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#primaryimage","url":"","contentUrl":""},{"@type":"BreadcrumbList","@id":"https:\/\/kapitalis.com\/tunisie\/2020\/12\/31\/le-vaccin-anti-covid-en-10-questions-reponses\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/kapitalis.com\/tunisie\/"},{"@type":"ListItem","position":2,"name":"Le vaccin anti-Covid en 10 questions-r\u00e9ponses"}]},{"@type":"WebSite","@id":"https:\/\/kapitalis.com\/tunisie\/#website","url":"https:\/\/kapitalis.com\/tunisie\/","name":"Kapitalis","description":"L'actualit\u00e9 en Tunisie et dans le monde","publisher":{"@id":"https:\/\/kapitalis.com\/tunisie\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/kapitalis.com\/tunisie\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/kapitalis.com\/tunisie\/#organization","name":"Kapitalis","url":"https:\/\/kapitalis.com\/tunisie\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/kapitalis.com\/tunisie\/#\/schema\/logo\/image\/","url":"https:\/\/kapitalis.com\/tunisie\/wp-content\/uploads\/2022\/05\/Kapitalis-big-size.png","contentUrl":"https:\/\/kapitalis.com\/tunisie\/wp-content\/uploads\/2022\/05\/Kapitalis-big-size.png","width":5000,"height":1500,"caption":"Kapitalis"},"image":{"@id":"https:\/\/kapitalis.com\/tunisie\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/KapitalisInfo\/","https:\/\/x.com\/KapitalisInfo","https:\/\/www.youtube.com\/channel\/UC-yDYrHyfFBWWZaOw3FPg9Q"]},{"@type":"Person","@id":"https:\/\/kapitalis.com\/tunisie\/#\/schema\/person\/d71f33a9ca44f7bad4698210b480c8e9","name":"webmaster kapitalis","url":"https:\/\/kapitalis.com\/tunisie\/author\/webmaster-kapitalis\/"}]}},"_links":{"self":[{"href":"https:\/\/kapitalis.com\/tunisie\/wp-json\/wp\/v2\/posts\/330386","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kapitalis.com\/tunisie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kapitalis.com\/tunisie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kapitalis.com\/tunisie\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/kapitalis.com\/tunisie\/wp-json\/wp\/v2\/comments?post=330386"}],"version-history":[{"count":0,"href":"https:\/\/kapitalis.com\/tunisie\/wp-json\/wp\/v2\/posts\/330386\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kapitalis.com\/tunisie\/wp-json\/wp\/v2\/media\/330387"}],"wp:attachment":[{"href":"https:\/\/kapitalis.com\/tunisie\/wp-json\/wp\/v2\/media?parent=330386"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kapitalis.com\/tunisie\/wp-json\/wp\/v2\/categories?post=330386"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kapitalis.com\/tunisie\/wp-json\/wp\/v2\/tags?post=330386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}