{"id":354451,"date":"2021-06-29T06:53:22","date_gmt":"2021-06-29T05:53:22","guid":{"rendered":"http:\/\/kapitalis.com\/tunisie\/?p=354451"},"modified":"2021-06-29T06:55:48","modified_gmt":"2021-06-29T05:55:48","slug":"linstitut-pasteur-de-tunis-oeuvre-au-detectage-des-variants-du-sars-cov-2","status":"publish","type":"post","link":"https:\/\/kapitalis.com\/tunisie\/2021\/06\/29\/linstitut-pasteur-de-tunis-oeuvre-au-detectage-des-variants-du-sars-cov-2\/","title":{"rendered":"L\u2019Institut Pasteur de Tunis \u0153uvre au d\u00e9tectage des variants du Sars-CoV-2"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" src=\"http:\/\/kapitalis.com\/tunisie\/wp-content\/uploads\/2021\/06\/Institut-Pasteur-de-Tunis-Sars-Cov-2.jpg\" alt=\"\" class=\"wp-image-354452\"\/><\/figure><\/div>\n\n\n\n<p><strong><em>Les \u00e9quipes de l\u2019Institut Pasteur de Tunis (IPT) travaillent ensemble, sous la coordination du\u00a0<a href=\"http:\/\/www.pasteur.tn\/index.php?option=com_content&amp;view=article&amp;id=184&amp;Itemid=544\" target=\"_blank\" rel=\"noreferrer noopener\">Laboratoire de virologie clinique<\/a> de l\u2019IPT, pour d\u00e9tecter des variants pr\u00e9occupants (\u00abvariants of concern\u00bb) et d\u2019int\u00e9r\u00eat (\u00abvariants of interest\u00bb) qui circulent d\u00e9j\u00e0 ou qui pourraient circuler actuellement en Tunisie.<\/em><\/strong><\/p>\n\n\n\n<!--more-->\n\n\n\n<p><br>Cette op\u00e9ration s\u2019inscrit dans le cadre de l\u2019effort national de surveillance mol\u00e9culaire du virus Sars-CoV-2.<\/p>\n\n\n\n<p>\u00c0 cette fin, le&nbsp;<a href=\"http:\/\/www.pasteur.tn\/index.php?option=com_content&amp;view=article&amp;id=184&amp;Itemid=544\" target=\"_blank\" rel=\"noreferrer noopener\">Laboratoire de Virologie Clinique<\/a>&nbsp;(LVC) et le Groupe \u00abImmunobiologie des infections\u00bb (GII) du <a href=\"http:\/\/www.pasteur.tn\/index.php?option=com_content&amp;view=article&amp;id=349:transmission-controle-et-immunobiologie-des-infections&amp;catid=88&amp;Itemid=702\" target=\"_blank\" rel=\"noreferrer noopener\">Laboratoire de recherche sur la transmission, contr\u00f4le et l\u2019immunobiologie des infections<\/a>\u00a0\u00bb (LTCII) ont mis en place une plateforme strat\u00e9gie de s\u00e9quen\u00e7age en deux temps avec un s\u00e9quen\u00e7age partiel dans le g\u00e8ne S en premier temps (LVC) suivi d\u2019un s\u00e9quen\u00e7age \u00e0 haut d\u00e9bit du g\u00e9nome complet (GII, LTCII) par la technologie MinION (Oxford Nanopore Technologies).<\/p>\n\n\n\n<p>Cette approche a permis de d\u00e9tecter pour la premi\u00e8re fois et entre autres l\u2019introduction du variant Alpha (B.117, appel\u00e9 Britannique) en f\u00e9vrier 2021 (Fares et al. 2021)* et l\u2019introduction du variant Delta (B.1.617.2, appel\u00e9 Indien) en juin 2021.<\/p>\n\n\n\n<p>La mise en place du s\u00e9quen\u00e7age \u00e0 haut d\u00e9bit sur le MinION a \u00e9t\u00e9 possible gr\u00e2ce au soutien du Fogarty International Center (instituts nationaux de sant\u00e9, Etats-Unis), de l\u2019Universit\u00e9 Johns Hopkins (Baltimore), et avec le support de la division internationale du R\u00e9seau international des instituts Pasteur et de la\u00a0<a href=\"http:\/\/www.pasteur.tn\/index.php?option=com_content&amp;view=article&amp;id=723&amp;Itemid=837\" target=\"_blank\" rel=\"noreferrer noopener\">Plateforme de technologie (IPTOmics) de l&rsquo;Institut Pasteur de Tunis.<\/a> \u00c0 titre indicatif et \u00e0 la date du 28 juin 2021, le variant Delta a \u00e9t\u00e9 retrouv\u00e9 chez 2<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.06.18.449083v1\" target=\"_blank\" rel=\"noreferrer noopener\">1 cas de Covid originaires de Kairouan, le Grand Tunis, Monastir et Siliana<\/a>.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Les \u00e9quipes de l\u2019Institut Pasteur de Tunis (IPT) travaillent ensemble, sous la coordination du\u00a0Laboratoire de virologie clinique de l\u2019IPT, pour d\u00e9tecter des variants pr\u00e9occupants (\u00abvariants of concern\u00bb) et d\u2019int\u00e9r\u00eat (\u00abvariants of interest\u00bb) qui circulent d\u00e9j\u00e0 ou qui pourraient circuler actuellement en Tunisie.<\/p>\n","protected":false},"author":8,"featured_media":354452,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[998,2433],"tags":[8909,91632,77508,91633,91519,91631],"class_list":["post-354451","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-societe","category-tunisie","tag-institut-pasteur-de-tunis","tag-laboratoire-de-virologie-clinique","tag-sars-cov-2","tag-variant-alpha","tag-variant-delta","tag-variants-preoccupants"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - 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